Sensor Systems for Biopharmaceutical Monitoring

: Label-Free and Multivariate Profiling of Cellular Products

• Biopharmaceuticals including cell, antibody, peptide, DNA, and protein needs to be monitored and assessed through various production process step to keep the consistent clinical outcome. This new type of 'drug' necessarily requires a new generation of non-destructive, label-free techniques that can characterize a single cell and their drug production at high-throughput, but otherwise leave it unadulterated before administration to the patient. 

• We are interested in the development of non-destructive and high-throughput analytic tools of cell therapy products using a label-free nanosensor technology, advanced hardware system, and AI analytics. Eventually, we hope to combine those tools into a continuous monitoring line enabled by each step of the feedback loop, and make a comprehensive biopharmaceutical monitoring platform for future therapeutics. We believe that this future patient-driven cell monitor will have a significantly short turnaround time and higher yields, so that eliminate the difference between each batch and show the consistent and improved clinical outcome.